The research team analyzed the saliva samples for levels of cortisol and measured the percentage changes in cutaneous microvascular perfusion. The protocol was repeated the following day using new patches. Participants returned at noon and 4:00 PM for further scans, and at the end of that time, the patches were removed. Saliva samples were collected, and questionnaires were completed. The next day, fingertip microvascular perfusion was measured, LEE or placebo patches were applied to participants' wrists, and perfusion scans were repeated, first immediately after and then 10 min after application of the patch.
Participants completed baseline psychological questionnaires and provided saliva samples for hormonal analysis. To obtain pilot data, 20 healthy individuals with no chronic conditions were recruited-5 males and 15 females-aged 30-69 y. Participants collected some of the saliva samples at work or home. Measurements were made in the laboratory at Mind-Body-Science (Tucson, AZ, USA). The study intended to assess the effects of LEE patches on salivary cortisol, peripheral circulation, and psychological measures on healthy adults.Ī double-blind, placebo-controlled, randomized pilot study was performed.
LifeWave Energy Enhancer (LEE) patches (LifeWave Corp, San Diego, CA, USA) on skin produce some changes that are consistent with increased energy production, but little is known about their effects on cortisol concentrations or the peripheral circulation.
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